GPUs are the oil of the AI boom—but you still can’t trade or hedge them.
YC S16 alum OneChronos has teamed up with Nobel-winner Paul Milgrom to launch the first marketplace for GPU futures, letting builders lock in prices, sell excess capacity, and fund the next wave of data centers.
https://lnkd.in/g28rCj92
Did AI kill creativity? Jialiang Zhou and Blake Shao built Stewdio (YC F24) to give creatives real control over AI-generated visuals.
Right now, image + video models and other generative tools are scattered across 10+ platforms. The typical turn-based chat interface makes organizing assets and ideas a mess.
Stewdio unifies the best generative AI models in one multiplayer canvas, letting creative teams produce stunning visuals with precision. You can create consistent characters, edit images wi ...more
Convexia (YC S25) is one of the most AGI-pilled ideas I've seen - an AI-maximalist pharma company. They use AI agents to find source drugs and design trials.
This is one of my favorite new company ideas. Pharma already spends almost all of its dollars figuring out what drugs to buy and then running trials with them. They do this with armies of human scientists. This can now be done with deep research AI agents.
If you're a pharma/biotech executive looking to in-license molecules, reach out to ...more
Convexia (YC S25) is an AI-maximalist pharma company that buys drugs, runs clinical trials, and sells them.
Pharma is a trillion-dollar industry with declining R&D productivity. Life-saving drugs are overlooked, abandoned, or shelved because diligence is still done by hand.
Convexia uses agents to operate 10x faster and 20x leaner.
Their AI agents autonomously handle:
- Sourcing: Find hidden preclinical assets
- Scientific diligence: Assess drug viability using computational biology
- Marke ...more
Cyberdesk (YC S25) is the computer use agent for developers to automate legacy Windows apps.
Developers in healthcare, supply chain, and other regulated industries struggle to integrate with customer EHRs, ERPs, and other legacy apps with poor APIs.
Today, they either hire unreliable offshore teams to click through remote desktops or try to build brittle scripts that break on popups and UI changes.
Cyberdesk makes it easy. Just write your task in plain English, and call their agent through an ...more
Decipher AI (YC W24)'s new AI agents watch every customer click in real time and surface bugs and frustrations long before support tickets roll in.
Dev velocity is soaring, yet most teams still spend days piecing together what is actually happening to real users: missing silent drop‑offs, painful errors, and UX bugs. The result? Churn, slipping NPS, and wasted engineering hours.
Decipher’s vision‑powered LLM agents watch every interaction in real time, flag frustrations and bugs the moment the ...more
OffDeal has just raised a $12M Series A to build the world’s first AI-native investment bank, bringing its total funding to $17M.
OffDeal is one of the pioneers of the "full stack AI startup.” Instead of selling AI to Goldman Sachs, OffDeal is building what Goldman itself would have looked like if it launched in 2025.
Wall Street's playbook works well, but only for billion-dollar deals - it breaks where most businesses actually exist. Traditional firms run oversized teams on outdated software, ...more
Jared Kaplan started out as a theoretical physicist chasing questions about the universe. Then he helped uncover one of AI’s most surprising truths: that intelligence scales in a predictable, almost physical way.
That insight became foundational to the modern era of large language models—and led him to co-found Anthropic.
In this talk from AI Startup School on June 16th, he walks through how that discovery reshaped the path to human-level AI, what it means for future models like Claude, and wh ...more
Lyra (YC X25) has just raised $6M in seed funding for its AI-native meeting platform built for sales teams.
The startup, founded by Courtne M. and Henry Kwon, wants to reinvent video calls—not just take notes from them. Instead of layering AI on top of Zoom or Meet, Lyra rebuilt the video conferencing platform itself, allowing teams to collaborate on-screen and get structured notes automatically.
Launched in late 2024, Lyra jumped from $20K to $700K in revenue in just six weeks and now powers ...more
Ari Malik and Mukund Tibrewala started Salient after Ari saw just how broken loan servicing was while working at Tesla: outdated systems, sky-high costs.
What began as a weekend project to automate loan servicing with voice AI quickly turned into something bigger: a fully integrated platform now used by fintechs and some of the biggest banks in the U.S.
In this conversation with YC Partner Diana Hu, the co-founders talk about cold emailing 500 lenders a day, landing Westlake Financial (a $25B ...more
Super cool demo. You can now just drop a few documents or prompts and generate a compelling explainer video. I could see this being useful for education, product onboarding, user training, and many other domains.
Congrats on the launch!
Courtyard.io just raised a $30M Series A to enable anyone to easily own and trade physical collectibles on the blockchain.
Founded in 2021 by ex-YouTube and Apple engineers Nicolas le Jeune and Paulin A., Courtyard pioneered a new model in the collectibles space: Digital Packs with instant buyback offers and a 0% fee marketplace.
Users can buy mystery packs of trading cards or comics online for a surprise item randomly selected from Courtyard’s vault. If customers don’t like what they get, th ...more
Golpo (YC S25) is the most powerful AI video generator for explainer videos from your documents or internal workflows. You can access the proprietary video generation engine through a simple web platform or integrate it via API.
To make videos today, you need to be an expert in video editing, sourcing, storyboarding, etc. While recent AI video tools are impressive at generating cinematic scenes or flashy content, they struggle with practical communication, like a product demo or a technical top ...more
Congrats to Salient on their $60 M Series A led by a16z! building AI agents for consumer loan servicing
they’re one of the fastest YC startups to get to 8-fig in rev I worked with, closing some of the largest U.S. banks just a few months after the batch
here’s how OSS foundation models powered their growth, and how sending 500 cold emails a day landed their first customers
Congrats Ari Malik Mukund Tibrewala !!
Ari discovered the idea at Tesla, where he learned loan‑servicing costs were high ...more
Verne Robotics has developed a SOTA model that lets robot arms to learn new skills in just 30 minutes (usually this takes days or weeks).
Their robot arms learn so quickly that they've unlocked entirely new business models for robot arms - e.g. renting them by-the-hour because so little upfront training is required. Check out their awesome video.
And I know these founders are much too humble to brag about it, but they were also one of the winners of YC's recent Product Showcase.
Congrats ...more
Webhound is an AI agent that builds datasets from the web.
Instead of visiting hundreds of websites and copying information into spreadsheets, users can now simply describe what they need and let the AI agent handle the rest.
Webhound automatically finds, extracts, and organizes web data into structured datasets you can export. It can visit LinkedIn profiles, watch YouTube videos, read Reddit threads, analyze e-commerce sites, and much more.
Some examples of Webhound prompts are:
- "Find 100 ...more
Verne Robotics has developed state-of-the-art models for controlling robot arms, allowing their arms to learn new skills in hours instead of weeks.
This enables a unique business model where they can let companies pay by-the-hour, instead of requiring massive capex. Verne Robotics already has a biotech unicorn using their robots in production to package icepacks and delicate chemical vials.
Traditional robot arms often require months of custom engineering and planning to integrate. These bulky ...more
Comena automates B2B order entry — from inbox to ERP — for distributors and manufacturers.
In industrial supply chains, sales reps still manually type in every purchase order and quote into their ERP. It eats up half their day and keeps them from actively selling.
Comena automates that entire workflow with AI agents. Just forward any PO— PDF, Excel, or email— and the AI extracts the right data, matches messy product descriptions to the right product numbers, and pushes it straight to your ERP. ...more
This is a real story of going from pivot hell to finding a $1B startup idea.
And the principle is true in general: very often, the right startup idea to work on is the one that you've already dismissed because it seemed too hard.